TRPS1, transcriptional repressor GATA binding 1

TRPS1, transcriptional repressor GATA binding 1

• This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq, Jul 2008]

• Gene Synonyms (zinc finger transcription factor Trps1, tricho-rhino-phalangeal syndrome type I protein, trichorhinophalangeal syndrome I, zinc finger protein GC79, GC79, LGCR,)
• NCBI Gene ID: 7227
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UHF7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transcriptional repressor GATA binding 1 interacts with:

• cell division cycle 16
  C-terminal binding protein 2
  cullin 7
  cyclin dependent kinase 2 associated protein 1
  dynein light chain LC8-type 1
  dynein light chain LC8-type 1
  forkhead box J2
  interleukin 17 receptor A
  metastasis associated 1
  myosin IC
  nemo like kinase
  potassium channel tetramerisation domain containing 5
  prolyl 4-hydroxylase subunit alpha 3
  SEC16 homolog A, endoplasmic reticulum export factor
  small ubiquitin like modifier 1
  TEA domain transcription factor 2
  tubulin, alpha 3A
  ubiquitin conjugating enzyme E2 I
  ubiquitin specific peptidase 4
  ubiquitously expressed prefoldin like chaperone
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.