UGCG, UDP-glucose ceramide glucosyltransferase

UGCG, UDP-glucose ceramide glucosyltransferase

• This gene encodes an enzyme that catalyzes the first glycosylation step in the biosynthesis of glycosphingolipids, which are membrane components containing lipid and sugar moieties. The product of this reaction is glucosylceramide, which is the core structure of many glycosphingolipids. [provided by RefSeq, Dec 2014]

• Gene Synonyms (ceramide glucosyltransferase, UDP-glucose:N-acylsphingosine D-glucosyltransferase, glucosylceramide synthase, GCS, GLCT1,)
• NCBI Gene ID: 7357
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R157
  UNIPROT ID#>>Q16739
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

UDP-glucose ceramide glucosyltransferase interacts with:

• CD83 molecule
  charged multivesicular body protein 4B
  HEPACAM family member 2
  melanocortin 2 receptor accessory protein 2
  protein interacting with PRKCA 1
  reticulon 3
  ring finger protein 123
  RUS family member 1
  tetraspanin 3
  TNF receptor superfamily member 10a
  TNF receptor superfamily member 10b
  transmembrane protein 231
  tripartite motif containing 25

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.