XRCC2, X-ray repair cross complementing 2

XRCC2, X-ray repair cross complementing 2

• This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. [provided by RefSeq, Jul 2008]

• Gene Synonyms (DNA repair protein XRCC2, X-ray repair complementing defective repair in Chinese hamster cells 2, X-ray repair cross-complementing protein 2, epididymis secretory sperm binding protein, FANCU,)
• NCBI Gene ID: 7516
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O43543
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

X-ray repair cross complementing 2 interacts with:

• ADP ribosylation factor like GTPase 4C
  dickkopf like acrosomal protein 1
  helicase, POLQ like
  mitochondrial ribosomal protein L50
  NADH:ubiquinone oxidoreductase complex assembly factor 5
  NFKB inhibitor interacting Ras like 1
  RAD51 paralog D
  WAP four-disulfide core domain 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.