ZNF189, zinc finger protein 189

ZNF189, zinc finger protein 189

• Kruppel-like zinc finger proteins such as ZNF189 contain a conserved stretch of 7 amino acids that connects a variable number of DNA-binding zinc finger repeats of the cys(2)his(2) (C2H2) type (summarized by Odeberg et al., 1998 [PubMed 9653648]). Approximately 30% of human Kruppel-like zinc finger proteins contain an N-terminal Kruppel-associated box (KRAB) domain. The KRAB domain consists of approximately 75 amino acids that may be subdivided into an A box, which is present in every KRAB domain and is essential for transcriptional repression, and a B box, which is not always present.[supplied by OMIM, May 2010]

• Gene Synonyms (zinc finger protein 189,)
• NCBI Gene ID: 7743
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B7ZLK9
  UNIPROT ID#>>O75820
  UNIPROT ID#>>A0A087X0K2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

zinc finger protein 189 interacts with:

• DGCR8 microprocessor complex subunit
  macroH2A.2 histone
  NOP53 ribosome biogenesis factor
  nucleolar protein 12
  proline rich 11

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.