KCNAB1, potassium voltage-gated channel subfamily A member regulatory beta subunit 1

KCNAB1, potassium voltage-gated channel subfamily A member regulatory beta subunit 1

• Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq, Apr 2015]

• Gene Synonyms (voltage-gated potassium channel subunit beta-1, K(+) channel subunit beta-1, K+ channel Beta1a chain, potassium channel beta 3 chain, potassium channel beta3 subunit, potassium channel shaker chain beta 1a, potassium channel, voltage gated subfamily A regulatory beta subunit 1, potassium voltage-gated channel, shaker-related subfamily, beta member 1, AKR6A3, KCNA1B, KV-BETA-1, Kvb1.3, hKvBeta3, hKvb3,)
• NCBI Gene ID: 7881
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B7Z8E5
  UNIPROT ID#>>F8W6W4
  UNIPROT ID#>>B7Z435
  UNIPROT ID#>>Q5MJQ3
  UNIPROT ID#>>Q14722
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

potassium voltage-gated channel subfamily A member regulatory beta subunit 1 interacts with:

• F-box protein 7
  NEDD4 like E3 ubiquitin protein ligase
  potassium voltage-gated channel subfamily A regulatory beta subunit 2
  receptor for activated C kinase 1
  solute carrier family 39 member 1
  solute carrier family 39 member 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.