POGLUT2, protein O-glucosyltransferase 2

POGLUT2, protein O-glucosyltransferase 2

• This gene encodes a protein product localized to the lumen of the endoplasmic reticulum. As a member of the endoplasmic reticulum protein family the encoded protein contains a Lys-Asp-Glu-Leu or KDEL motif located at the extreme C-terminus which prevents all endoplasmic reticulum resident proteins from being secreted. Proteins carrying this motif are bound by a receptor in the Golgi apparatus so that the receptor-ligand complex returns to the endoplasmic reticulum. A processed non-transcribed pseudogene located in an intron of a sodium transporter gene on chromosome 5 has been defined for this gene. This gene has multiple transcript variants which are predicted to encode distinct isoforms. [provided by RefSeq, Jan 2016]

• Gene Synonyms (protein O-glucosyltransferase 2, ER protein 58, KDEL (Lys-Asp-Glu-Leu) containing 1, KDEL motif containing 1, KDEL motif-containing protein 1, endoplasmic reticulum resident protein 58, protein O-xylosyltransferase POGLUT2, EP58, ERp58, KDEL1, KDELC1,)
• NCBI Gene ID: 79070
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6UW63
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein O-glucosyltransferase 2 interacts with:

• ankyrin repeat domain 28
  lysyl oxidase like 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.