FYCO1, FYVE and coiled-coil domain autophagy adaptor 1

FYCO1, FYVE and coiled-coil domain autophagy adaptor 1

• This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2). [provided by RefSeq, Dec 2011]

• Gene Synonyms (FYVE and coiled-coil domain-containing protein 1, FYVE and coiled-coil domain containing 1, RUN and FYVE domain containing 3, zinc finger FYVE domain-containing protein 7, CATC2, CTRCT18, RUFY3, ZFYVE7,)
• NCBI Gene ID: 79443
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BQS8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

FYVE and coiled-coil domain autophagy adaptor 1 interacts with:

• 2-aminoethanethiol dioxygenase
  coiled-coil domain containing 68
  DNA polymerase delta interacting protein 3
  forkhead box K1
  integrin alpha FG-GAP repeat containing 1
  microtubule associated protein 1 light chain 3 alpha
  microtubule associated protein 1 light chain 3 beta
  nucleolar protein 9
  RFT1 homolog
  SAGA complex associated factor 29
  SAS-6 centriolar assembly protein
  t-complex 10 like

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.