SRD5A3, steroid 5 alpha-reductase 3

SRD5A3, steroid 5 alpha-reductase 3

• The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq. [provided by RefSeq, Mar 2011]

• Gene Synonyms (polyprenol reductase, 3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)), 3-oxo-5-alpha-steroid 4-dehydrogenase 3, S5AR 3, SR type 3, probable polyprenol reductase, CDG1P, CDG1Q, KRIZI, SRD5A2L, SRD5A2L1,)
• NCBI Gene ID: 79644
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H8P0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

steroid 5 alpha-reductase 3 interacts with:

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