ICE2, interactor of little elongation complex ELL subunit 2

ICE2, interactor of little elongation complex ELL subunit 2

• This gene encodes a protein component of the little elongation complex (LEC), which plays a role in small nuclear RNA (snRNA) transcription. The LEC regulates snRNA transcription by enhancing both RNA Polymerase II occupancy and transcriptional elongation. The encoded protein and other LEC components have been shown to localize to Cajal bodies, which are sites of ribonucleoprotein (RNP) complex assembly. Pseudogenes of this gene have been identified on chromosomes 3 and 4. [provided by RefSeq, May 2017]

• Gene Synonyms (little elongation complex subunit 2, NMDA receptor regulated 2, NMDA receptor-regulated gene 2, NMDA receptor-regulated protein 2, breast cancer cell 1, interactor of little elongator complex ELL subunit 2, BRCC1, NARG2,)
• NCBI Gene ID: 79664
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R5V9
  UNIPROT ID#>>H0YNU9
  UNIPROT ID#>>Q659A1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

interactor of little elongation complex ELL subunit 2 interacts with:

• ankyrin repeat domain 26
  DSN1 component of MIS12 kinetochore complex
  ELL associated factor 1
  elongation factor for RNA polymerase II 3
  integrator complex subunit 14
  mucin 5B, oligomeric mucus/gel-forming
  suppressor of cancer cell invasion
  suppressor of IKBKE 1
  thyroid hormone receptor interactor 11
  zymogen granule protein 16B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.