TFPI2, tissue factor pathway inhibitor 2

TFPI2, tissue factor pathway inhibitor 2

• This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

• Gene Synonyms (tissue factor pathway inhibitor 2, placental protein 5, retinal pigment epithelium cell factor 1, PP5, REF1, TFPI-2,)
• NCBI Gene ID: 7980
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P48307
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tissue factor pathway inhibitor 2 interacts with:

• cyclic GMP-AMP synthase
  SMAD specific E3 ubiquitin protein ligase 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.