CPSF7, cleavage and polyadenylation specific factor 7

CPSF7, cleavage and polyadenylation specific factor 7

• Cleavage factor Im (CFIm) is one of six factors necessary for correct cleavage and polyadenylation of pre-mRNAs. CFIm is composed of three different subunits of 25, 59, and 68 kDa, and it functions as a heterotetramer, with a dimer of the 25 kDa subunit binding to two of the 59 or 68 kDa subunits. The protein encoded by this gene represents the 59 kDa subunit, which can interact with the splicing factor U2 snRNP Auxiliary Factor (U2AF) 65 to link the splicing and polyadenylation complexes. [provided by RefSeq, Oct 2016]

• Gene Synonyms (cleavage and polyadenylation specificity factor subunit 7, CPSF 59 kDa subunit, cleavage and polyadenylation specificity factor 59 kDa subunit, cleavage factor Im complex 59 kDa subunit, pre-mRNA cleavage factor I, 59 kDa subunit, pre-mRNA cleavage factor Im 59 kDa subunit, CFIm59,)
• NCBI Gene ID: 79869
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DGF8
  UNIPROT ID#>>Q8N684
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cleavage and polyadenylation specific factor 7 interacts with:

• B9 domain containing 2
  cation channel sperm associated 1
  cilia and flagella associated protein 206
  cyclin Q
  guanylyl cyclase domain containing 1
  itchy E3 ubiquitin protein ligase
  leukocyte receptor cluster member 8
  ligand of numb-protein X 1
  proteasome activator subunit 3 interacting protein 1
  RIO kinase 1
  sorting nexin 18
  zinc finger protein 766

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.