SCD5, stearoyl-CoA desaturase 5

SCD5, stearoyl-CoA desaturase 5

• Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Wang et al., 2005 [PubMed 15907797]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (stearoyl-CoA desaturase 5, acyl-CoA-desaturase 4, stearoyl-CoA 9-desaturase, stearoyl-CoA desaturase 2, stearoyl-CoA desaturase 4, ACOD4, FADS4, HSCD5, SCD2, SCD4,)
• NCBI Gene ID: 79966
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86SK9
  UNIPROT ID#>>Q86UC8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

stearoyl-CoA desaturase 5 interacts with:

• carnosine dipeptidase 1

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