STN1, STN1 subunit of CST complex

STN1, STN1 subunit of CST complex

• OBFC1 and C17ORF68 (MIM 613129) are subunits of an alpha accessory factor (AAF) that stimulates the activity of DNA polymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication (Casteel et al., 2009 [PubMed 19119139]). OBFC1 also appears to function in a telomere-associated complex with C17ORF68 and TEN1 (C17ORF106; MIM 613130) (Miyake et al., 2009 [PubMed 19854130]).[supplied by OMIM, Nov 2009]

• Gene Synonyms (CST complex subunit STN1, STN1, CST complex subunit, alpha accessory factor 44, oligonucleotide/oligosaccharide binding fold containing 1, oligonucleotide/oligosaccharide-binding fold-containing protein 1, replication protein A 32 kDa subunit, suppressor of cdc thirteen homolog, AAF-44, AAF44, OBFC1, RPA-32, bA541N10.2,)
• NCBI Gene ID: 79991
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H668
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

STN1 subunit of CST complex interacts with:

• actin related protein 3C
  CST telomere replication complex component 1
  family with sequence similarity 136 member A
  heterogeneous nuclear ribonucleoprotein A3
  leucine rich repeat kinase 2
  leucine rich repeats and WD repeat domain containing 1
  lysophospholipase-like 1
  mediator complex subunit 25
  mediator complex subunit 30
  mediator complex subunit 8
  NSE1 homolog, SMC5-SMC6 complex component
  shieldin complex subunit 1
  single-pass membrane protein with coiled-coil domains 3
  TEN1 subunit of CST complex
  tripartite motif family like 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.