FRAS1, Fraser extracellular matrix complex subunit 1

FRAS1, Fraser extracellular matrix complex subunit 1

• This gene encodes an extracellular matrix protein that appears to function in the regulation of epidermal-basement membrane adhesion and organogenesis during development. Mutations in this gene cause Fraser syndrome, a multisystem malformation that can include craniofacial, urogenital and respiratory system abnormalities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

• Gene Synonyms (extracellular matrix protein FRAS1, Fraser syndrome 1, FRASRS1,)
• NCBI Gene ID: 80144
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86XX4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Fraser extracellular matrix complex subunit 1 interacts with:

• glycoprotein hormone subunit alpha 2
  interferon epsilon
  leucine rich repeat transmembrane neuronal 1
  lipase H
  lysozyme like 1
  pregnancy specific beta-1-glycoprotein 8
  X antigen family member 1A
  ZFP41 zinc finger protein
  zona pellucida binding protein 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.