ULBP1, UL16 binding protein 1

ULBP1, UL16 binding protein 1

• The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

• Gene Synonyms (UL16-binding protein 1, NKG2D ligand 1, alcan-beta, retinoic acid early transcript 1I, N2DL-1, NKG2DL1, RAET1I,)
• NCBI Gene ID: 80329
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BZM6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

UL16 binding protein 1 interacts with:

• immunoglobulin lambda like polypeptide 5
  membrane associated ring-CH-type finger 9
  retinoic acid early transcript 1G
  solute carrier family 39 member 5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.