FGF23, fibroblast growth factor 23

FGF23, fibroblast growth factor 23

• This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013]

• Gene Synonyms (fibroblast growth factor 23, phosphatonin, tumor-derived hypophosphatemia inducing factor, ADHR, FGFN, HFTC2, HPDR2, HYPF, PHPTC,)
• NCBI Gene ID: 8074
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9GZV9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

fibroblast growth factor 23 interacts with:

• klotho

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.