COLEC12, collectin subfamily member 12

COLEC12, collectin subfamily member 12

• This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells. [provided by RefSeq, May 2018]

• Gene Synonyms (collectin-12, collectin placenta protein 1, collectin sub-family member 12, hCL-P1, nurse cell scavenger receptor 2, scavenger receptor class A, member 4, scavenger receptor with C-type lectin, CLP1, NSR2, SCARA4, SRCL,)
• NCBI Gene ID: 81035
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5KU26
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

collectin subfamily member 12 interacts with:

• C1q and TNF related 2
  C-type lectin domain family 12 member A
  FERM domain containing 3
  IKBKB interacting protein
  killer cell lectin like receptor G2
  lectin, mannose binding 2 like
  thioredoxin related transmembrane protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.