H2BC6, H2B clustered histone 6

H2BC6, H2B clustered histone 6

• Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. The protein has antibacterial and antifungal antimicrobial activity. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]

• Gene Synonyms (histone H2B type 1-C/E/F/G/I, H2B histone family, member H, histone 1, H2be, histone H2B.1 A, histone H2B.h, histone cluster 1 H2B family member e, histone cluster 1, H2be, H2B.h, H2B/h, H2BC10, H2BC4, H2BC7, H2BC8, H2BFH, HIST1H2BE, dJ221C16.8,)
• NCBI Gene ID: 8344
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P62807
  UNIPROT ID#>>B2R4S9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

H2B clustered histone 6 interacts with:

• immunoglobulin superfamily member 8
  RIO kinase 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.