RSPH3, radial spoke head 3

RSPH3, radial spoke head 3

• The protein encoded by this gene acts as a protein kinase A anchoring protein. Mutations in this gene cause primary ciliary dyskinesia; a disorder characterized by defects of the axoneme in motile cilia and sperm flagella. The homolog of this gene was first identified in the blue-green algae Chlamydomonas as encoding a radial spoke protein that formed a structural component of motile cilia and flagella. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2016]

• Gene Synonyms (radial spoke head protein 3 homolog, A-kinase anchor protein RSPH3, radial spoke 3 homolog, radial spoke head 3 homolog, radial spoke head-like protein 2, CILD32, RSHL2, RSP3, dJ111C20.1,)
• NCBI Gene ID: 83861
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86UC2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

radial spoke head 3 interacts with:

• dpy-30 histone methyltransferase complex regulatory subunit

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.