ANXA9, annexin A9

ANXA9, annexin A9

• The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. This gene encodes a divergent member of the annexin protein family in which all four homologous type II calcium-binding sites in the conserved tetrad core contain amino acid substitutions that ablate their function. However, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact. [provided by RefSeq, Jul 2008]

• Gene Synonyms (annexin A9, annexin 31, annexin XXXI, annexin-9, pemphaxin, ANX31,)
• NCBI Gene ID: 8416
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O76027
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

annexin A9 interacts with:

• ETAA1 activator of ATR kinase
  NDUFA4 mitochondrial complex associated like 2
  Rho guanine nucleotide exchange factor 10 like
  tripartite motif containing 69

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.