HOPX, HOP homeobox

HOPX, HOP homeobox

• The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Feb 2009]

• Gene Synonyms (homeodomain-only protein, lung cancer-associated Y protein, not expressed in choriocarcinoma clone 1, odd homeobox protein 1, CAMEO, HOD, HOP, LAGY, NECC1, OB1, SMAP31, TOTO,)
• NCBI Gene ID: 84525
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BPY8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

HOP homeobox interacts with:

• zinc finger and SCAN domain containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.