GNPTG, N-acetylglucosamine-1-phosphate transferase subunit gamma

GNPTG, N-acetylglucosamine-1-phosphate transferase subunit gamma

• This gene encodes the gamma sunbunit of the N-acetylglucosamine-1-phosphotransferase complex. This hexameric complex, composed of alpha, beta and gamma subunits, catalyzes the first step in synthesis of a mannose 6-phosphate lysosomal recognition marker. This enzyme complex is necessary for targeting of lysosomal hydrolases to the lysosome. Mutations in the gene encoding the gamma subunit have been associated with mucolipidosis IIIC, also known as mucolipidosis III gamma.[provided by RefSeq, Feb 2010]

• Gene Synonyms (N-acetylglucosamine-1-phosphotransferase subunit gamma, N-acetylglucosamine-1-phosphate transferase gamma subunit, UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma, glcNAc-1-phosphotransferase subunit gamma, C16orf27, GNPTAG, LP2537, RJD9,)
• NCBI Gene ID: 84572
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UJJ9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

N-acetylglucosamine-1-phosphate transferase subunit gamma interacts with:

• anaphase promoting complex subunit 2
  reticulophagy regulator family member 3
  splA/ryanodine receptor domain and SOCS box containing 3
  transmembrane protein 25
  zona pellucida like domain containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.