PLA2G12B, phospholipase A2 group XIIB

PLA2G12B, phospholipase A2 group XIIB

• The protein encoded by this gene belongs to the phospholipase A2 (PLA2) group of enzymes, which function in glycolipid hydrolysis with the release of free fatty acids and lysophospholipids. This family member has altered phospholipid-binding properties and is catalytically inactive. The protein is secreted, and together with microsomal triglyceride transfer protein, it functions to regulate HNF4alpha-induced hepatitis C virus infectivity. The expression of this gene is down-regulated in various tumors, suggesting that it may function as a negative regulator of tumor progression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]

• Gene Synonyms (group XIIB secretory phospholipase A2-like protein, group XIII secreted phospholipase A2, phospholipase A2, group XIII, FKSG71, GXIIB, GXIIIsPLA2, PLA2G13, sPLA2-GXIIB,)
• NCBI Gene ID: 84647
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BX93
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phospholipase A2 group XIIB interacts with:

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