DOCK7, dedicator of cytokinesis 7

DOCK7, dedicator of cytokinesis 7

• The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that plays a role in axon formation and neuronal polarization. The encoded protein displays GEF activity toward RAC1 and RAC3 Rho small GTPases but not toward CDC42. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

• Gene Synonyms (dedicator of cytokinesis protein 7, EIEE23, ZIR2,)
• NCBI Gene ID: 85440
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96N67
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

dedicator of cytokinesis 7 interacts with:

• egl-9 family hypoxia inducible factor 3
  kelch domain containing 9
  MOB kinase activator 1B
  protein phosphatase 1 regulatory subunit 18
  Ras association domain family member 10
  zinc finger protein 785

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.