SELENOI, selenoprotein I

SELENOI, selenoprotein I

• The multi-pass transmembrane protein encoded by this gene belongs to the CDP-alcohol phosphatidyltransferase class-I family. It catalyzes the transfer of phosphoethanolamine from CDP-ethanolamine to diacylglycerol to produce phosphatidylethanolamine, which is involved in the formation and maintenance of vesicular membranes, regulation of lipid metabolism, and protein folding. This protein is a selenoprotein, containing the rare selenocysteine (Sec) amino acid at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2016]

• Gene Synonyms (ethanolaminephosphotransferase 1, ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific), hEPT1, EPT1, SELI, SEPI, SPG81,)
• NCBI Gene ID: 85465
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9C0D9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

selenoprotein I interacts with:

• metadherin

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