SCARF1, scavenger receptor class F member 1

SCARF1, scavenger receptor class F member 1

• The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells. It regulates the uptake of chemically modified low density lipoproteins, including acetylated low density lipoprotein (Ac-LDL), and it may be involved in atherogenesis. This gene is regulated by the transcription factors ZNF444/EZF-2 and SP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]

• Gene Synonyms (scavenger receptor class F member 1, acetyl LDL receptor, scavenger receptor expressed by endothelial cells 1, SREC, SREC-I, SREC1,)
• NCBI Gene ID: 8578
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q14162
  UNIPROT ID#>>A8K6Z5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

scavenger receptor class F member 1 interacts with:

• cAMP responsive element binding protein 3 like 1
  coenzyme Q9
  cysteine rich tail 1
  family with sequence similarity 209 member A
  G protein-coupled receptor 37 like 1
  glutathione peroxidase 8 (putative)
  hydroxysteroid 17-beta dehydrogenase 13
  keratin associated protein 10-8
  keratin associated protein 1-1
  keratin associated protein 5-7
  late cornified envelope 1D
  LHFPL tetraspan subfamily member 2
  mitochondrial rRNA methyltransferase 3
  nuclear envelope integral membrane protein 1
  scavenger receptor class F member 2
  solute carrier family 7 member 14

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.