ADAM19, ADAM metallopeptidase domain 19

ADAM19, ADAM metallopeptidase domain 19

• This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease. [provided by RefSeq, May 2013]

• Gene Synonyms (disintegrin and metalloproteinase domain-containing protein 19, a disintegrin and metalloproteinase domain 19 (meltrin beta), metalloprotease and disintegrin dendritic antigen marker, metalloprotease-disintegrin meltrin beta, FKSG34, MADDAM, MLTNB,)
• NCBI Gene ID: 8728
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8TBU7
  UNIPROT ID#>>Q9H013
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ADAM metallopeptidase domain 19 interacts with:

• abl interactor 2
  ESF1 nucleolar pre-rRNA processing protein homolog

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