PLCZ1, phospholipase C zeta 1

PLCZ1, phospholipase C zeta 1

• The protein encoded by this gene is a member of the phosphoinositide-specific phospholipase C family. Members in this family, classified into six isotypes that are tissue- and organ-specific, hydrolyze phosphatidylinositol 4,5-bisphosphate just before the phosphate group to yield diacylglycerol and inositol 1,4,5-trisphosphate. This protein localizes to the acrosome in spermatozoa and elicits Ca(2+) oscillations and egg activation during fertilization that leads to early embryonic development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

• Gene Synonyms (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1, PI-phospholipase C zeta 1, phosphoinositide phospholipase C-zeta-1, testicular tissue protein Li 145, testis-development related NYD-SP27, NYD-SP27, PLC-zeta-1, PLCzeta, SPGF17,)
• NCBI Gene ID: 89869
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86YW0
  UNIPROT ID#>>A0A140VJR9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phospholipase C zeta 1 interacts with:

• serpin family A member 12

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.