TNFSF18, TNF superfamily member 18

TNFSF18, TNF superfamily member 18

• The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq, Jul 2008]

• Gene Synonyms (tumor necrosis factor ligand superfamily member 18, AITR ligand, GITR ligand, activation-inducible TNF-related ligand, glucocorticoid-induced TNF-related ligand, glucocorticoid-induced TNFR-related protein ligand, tumor necrosis factor (ligand) superfamily, member 18, tumor necrosis factor ligand 2A, tumor necrosis factor superfamily member 18, AITRL, GITRL, TL6, TNLG2A, hGITRL,)
• NCBI Gene ID: 8995
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UNG2
  UNIPROT ID#>>A0A0U5JXL4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TNF superfamily member 18 interacts with:

• exocyst complex component 3 like 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.