LDB2, LIM domain binding 2

LDB2, LIM domain binding 2

• The protein encoded by this gene belongs to the LIM-domain binding family. Members of this family are characterized by a conserved nuclear localization sequence, an amino-terminal homodimerization domain and a carboxy-terminal LIM interaction domain. These proteins function as adapter molecules to allow assembly of transcriptional regulatory complexes. Genetic association studies suggest functions for this gene in rhegmatogenous retinal detachment and coronary artery disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

• Gene Synonyms (LIM domain-binding protein 2, LIM binding domain 2, LIM domain-binding factor CLIM1, LIM domain-binding factor-2, carboxyl-terminal LIM domain-binding protein 1, CLIM1, LDB-2, LDB1,)
• NCBI Gene ID: 9079
• Species: Homo sapiens (Human)
• UNIPROT ID#>>G5E9Y7
  UNIPROT ID#>>E9PFI4
  UNIPROT ID#>>O43679
  UNIPROT ID#>>B7Z6D0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

LIM domain binding 2 interacts with:

• chromosome 14 open reading frame 119
  DiGeorge syndrome critical region gene 6 like
  egl-9 family hypoxia inducible factor 3
  EPM2A interacting protein 1
  exocyst complex component 3 like 1
  gamma-glutamylamine cyclotransferase
  histone deacetylase 7
  ligand of numb-protein X 1
  LIM domain only 3
  LIM homeobox 4
  LIM homeobox 8
  LIM homeobox 9
  N-terminal glutamine amidase 1
  Rab interacting lysosomal protein
  Ras interacting protein 1
  ring finger protein, LIM domain interacting
  single stranded DNA binding protein 2
  single stranded DNA binding protein 3
  single stranded DNA binding protein 4
  tetratricopeptide repeat domain 19

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.