TBX19, T-box transcription factor 19

TBX19, T-box transcription factor 19

• This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure. [provided by RefSeq, Jul 2008]

• Gene Synonyms (T-box transcription factor TBX19, T-box 19, T-box factor, pituitary, T-box protein 19, TBS 19, TBS19, TPIT, dJ747L4.1,)
• NCBI Gene ID: 9095
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O60806
  UNIPROT ID#>>B3KRD9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

T-box transcription factor 19 interacts with:

• glial cells missing transcription factor 2
  hepatocyte growth factor-regulated tyrosine kinase substrate
  iroquois homeobox 6
  LON peptidase N-terminal domain and ring finger 1
  pogo transposable element derived with ZNF domain
  proline rich 35
  RAB2B, member RAS oncogene family
  trafficking from ER to golgi regulator
  VENT homeobox

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.