DDX60L, DExD/H-box 60 like

DDX60L, DExD/H-box 60 like

• This gene encodes a member of the DExD/H-box helicase family of proteins, a subset of the super family 2 helicases. Members of the DExD/H-box helicase family share a conserved functional core comprised of two RecA-like globular domains. These domains contain conserved motifs that mediate ATP binding, ATP hydrolysis, nucleic acid binding, and RNA unwinding. In addition to functions in RNA metabolism, members of this family are involved in anti-viral immunity and act as cytosolic sensors of viral nucleic acids. The protein encoded by this gene has been shown to inhibit hepatitis C virus replication in response to interferon stimulation in cell culture. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

• Gene Synonyms (probable ATP-dependent RNA helicase DDX60-like, DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like, DEAD box protein 60-like, DEAD-box helicase 60 like, putative ATP-dependent RNA helicase DDX60,)
• NCBI Gene ID: 91351
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5H9U9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DExD/H-box 60 like interacts with:

• cyclic GMP-AMP synthase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.