ATP23, ATP23 metallopeptidase and ATP synthase assembly factor homolog

ATP23, ATP23 metallopeptidase and ATP synthase assembly factor homolog

• The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

• Gene Synonyms (mitochondrial inner membrane protease ATP23 homolog, Ku70-binding protein 3, XRCC6-binding protein 1, KUB3, XRCC6BP1,)
• NCBI Gene ID: 91419
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y6H3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ATP23 metallopeptidase and ATP synthase assembly factor homolog interacts with:

• alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
  exocyst complex component 8
  glycerate kinase
  keratin associated protein 10-1
  kinesin light chain 3
  nucleoporin 35

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.