UBXN11, UBX domain protein 11

UBXN11, UBX domain protein 11

• This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (UBX domain-containing protein 11, UBX domain-containing protein 5, colorectal tumor-associated antigen COA-1, colorectal tumor-associated antigen-1, socius, COA-1, PP2243, SOC, SOCI, UBXD5,)
• NCBI Gene ID: 91544
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5T124
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

UBX domain protein 11 interacts with:

• cilia and flagella associated protein 206
  proline rich 35
  protein phosphatase, Mg2+/Mn2+ dependent 1K
  transcription elongation factor A N-terminal and central domain containing

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.