EXO1, exonuclease 1

EXO1, exonuclease 1

• This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq, Jul 2008]

• Gene Synonyms (exonuclease 1, rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1, HEX1, hExoI,)
• NCBI Gene ID: 9156
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A8K5H6
  UNIPROT ID#>>Q9UQ84
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

exonuclease 1 interacts with:

• actin related protein 5
  DDB1 and CUL4 associated factor 1
  egl-9 family hypoxia inducible factor 3
  kinesin light chain 3
  myelin expression factor 2
  SUMO specific peptidase 6
  transmembrane protein 109
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  WD repeat domain 83

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.