H2AZ2, H2A.Z variant histone 2

H2AZ2, H2A.Z variant histone 2

• Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. Several transcript variants encoding different isoforms, have been identified for this gene. [provided by RefSeq, Oct 2015]

• Gene Synonyms (H2A.Z-2, H2AFV, H2AV, histone H2A.V, H2A histone family member V, H2A.F/Z, histone H2A.F/Z, purine-rich binding element protein B,)
• NCBI Gene ID: 94239
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q71UI9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

H2A.Z variant histone 2 interacts with:

• armadillo repeat containing 12
  cullin 4A
  deltex E3 ubiquitin ligase 3L

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.