RIPOR2, RHO family interacting cell polarization regulator 2

RIPOR2, RHO family interacting cell polarization regulator 2

• This gene encodes an atypical inhibitor of the small G protein RhoA. Inhibition of RhoA activity by the encoded protein mediates myoblast fusion and polarization of T cells and neutrophils. The encoded protein is a component of hair cell stereocilia that is essential for hearing. A splice site mutation in this gene results in hearing loss in human patients. [provided by RefSeq, Sep 2016]

• Gene Synonyms (rho family-interacting cell polarization regulator 2, family with sequence similarity 65 member B, myogenesis-related and NCAM-associated protein homolog, protein FAM65B, C6orf32, DFNB104, DIFF40, DIFF48, FAM65B, MYONAP, PL48,)
• NCBI Gene ID: 9750
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024QZY9
  UNIPROT ID#>>B7Z6U4
  UNIPROT ID#>>A0A024R028
  UNIPROT ID#>>B7Z6D6
  UNIPROT ID#>>B7Z5J9
  UNIPROT ID#>>F5H029
  UNIPROT ID#>>Q9Y4F9
  UNIPROT ID#>>F5GX51
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RHO family interacting cell polarization regulator 2 interacts with:

• histone deacetylase 6
  myoferlin

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.