LRIG2, leucine rich repeats and immunoglobulin like domains 2

LRIG2, leucine rich repeats and immunoglobulin like domains 2

• This gene encodes a transmembrane protein containing leucine-rich repeats and immunoglobulin-like domains. The encoded protein promotes epidermal growth factor signalling, resulting in increased proliferation. Its expression in the cytoplasm of glioma cells is correlated with poor survival. Mutations in this gene can cause urofacial syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

• Gene Synonyms (leucine-rich repeats and immunoglobulin-like domains protein 2, LIG-2, LIG2, UFS2,)
• NCBI Gene ID: 9860
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O94898
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

leucine rich repeats and immunoglobulin like domains 2 interacts with:

• F-box protein 6
  leucine rich repeats and immunoglobulin like domains 1
  OTU deubiquitinase with linear linkage specificity like

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.