REC8, REC8 meiotic recombination protein

REC8, REC8 meiotic recombination protein

• This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (meiotic recombination protein REC8 homolog, REC8 homolog, REC8-like 1, cohesin Rec8p, cohesion rec8p, human homolog of rad21, S. pombe, kleisin-alpha, meiotic recombination and sister chromatid cohesion phosphoprotein of the rad21p family, meiotic recombination protein REC8-like 1, recombination and sister chromatid cohesion protein homolog, HR21spB, REC8L1, Rec8p,)
• NCBI Gene ID: 9985
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O95072
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

REC8 meiotic recombination protein interacts with:

• structural maintenance of chromosomes 1B
  synaptonemal complex protein 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.