Some samples, such as tissue and hair, require pretreatment with proteinase K. In addition, extracting DNA can be difficult from substrates such as denim, envelopes, carpet, etc. The Tissue and Hair Extraction Kit increases DNA yield from challenging casework samples and substrates. The kit uses Proteinase K and other reagents to remove proteins and other components from the DNA, helping to ensure maximal yield and recovery of DNA from casework samples. The DNA then can be purified using the DNA IQ™ System, the DNA IQ™ Casework Pro Kit for Maxwell® 16 or the Maxwell® FSC DNA IQ™ Casework Kit.