Cell Line |
Citation |
A549 |
Somensi, N., et al. (2017) Extracellular HSP70 Activates ERK1/2, NF-kB and Pro-Inflammatory Gene Transcription Through Binding with RAGE in A549 Human Lung Cancer Cells. Cell. Physiol. Biochem. 42, 2507-22. |
AF22 |
Chai, M., et al. (2018) Chromatin remodeler CHD7 regulates the stem cell identity of human neural progenitors. Genes Dev. 32, 165-80. |
AGS |
Cerda-Opazo, P., et al. (2018) Inverse expression of survivin and reprimo correlates with poor patient prognosis in gastric cancer. Oncotarget 9, 12853-67. |
AU565 |
Bagu, E.T., et al. (2017) Repression of Fyn-related kinase in breast cancer cells is associated with promoter site-specific CpG methylation. Oncotarget 8, 11442-59. |
B16F0 |
Morita, T. and Hayashi, K. (2018) Tumor progression is mediated by thymosin-β4 through a TGFβ/MRTF signaling axis. Mol. Cancer Res. 16, 880-93. |
B16F1 |
Morita, T. and Hayashi, K. (2018) Tumor progression is mediated by thymosin-β4 through a TGFβ/MRTF signaling axis. Mol. Cancer Res. 16, 880-93. |
BJ1-7TGP |
Kramer, N., et al. (2017) Autocrine WNT2 signaling in fibroblasts promotes colorectal cancer progression. Oncogene 36, 5460-72. |
Bovine Aortic
Endothelial Cells |
Gupta, R.M., et al. (2017) A genetic variant associated with five vascular diseases is a distal regulator of endothelin-1 gene expression. Cell 170, 522-33. |
BT |
Alkheraif, A.A., et al. (2017) Type 2 BVDV Npro suppresses IFN-1 pathway signaling in bovine cells and augments BRSV replication. Virology 507, 123-34. |
C2C12 |
Saklayen, N., et al. (2017) Analysis of poration-induced changes in cells from laser-activated plasmonic substrates. Biomed. Opt. Express 8, 4756-71. |
CHO |
Hoonakker, M.E., et al. (2017) Reporter cell lines for detection of pertussis toxin in acellular pertussis vaccines as a functional animal-free alternative to the in vivo histamine sensitization test. Vaccine 35, 1152-60. |
COS-7 |
Nakagawa, T., et al. (2017) N-glycan-dependent cell-surface expression of the P2Y2 receptor and N-glycan-independent distribution to lipid rafts. Biochem. Biophys. Res. Comm. 485, 427-31. |
COV-504 |
Lu, T., et al. (2018) Blockade of ONECUT2 expression in ovarian cancer inhibited tumor cell proliferation, migration, invasion and angiogenesis. Cancer Sci. 109, 2221-34. |
EH-GB1 |
Ma, Q., et al. (2018) EMP3, which is regulated by miR-663a, suppresses gallbladder cancer progression via interference with the MAPK/ERK pathway. Cancer Lett. 430, 97-108. |
EH-GB1 |
Hao, J., et al. (2017) Downregulation of BRD4 inhibits gallbladder cancer proliferation and metastasis and induces apoptosis via PI3K/AKT pathway. Int. J. Oncol. 51, 823-32 |
GBC-SD |
Ma, Q., et al. (2018) EMP3, which is regulated by miR-663a, suppresses gallbladder cancer progression via interference with the MAPK/ERK pathway. Cancer Lett. 430, 97-108. |
GBC-SD |
Hao, J., et al. (2017) Downregulation of BRD4 inhibits gallbladder cancer proliferation and metastasis and induces apoptosis via PI3K/AKT pathway. Int. J. Oncol. 51, 823-33 |
GIST882 |
Wang, L., et al.(2017) Orai1 mediates tumor-promoting store-operated Ca2+ entry in human gastrointestinal stromal tumors via c-KIT and the extracellular signal–regulated kinase pathway. Tumor Biol. 39, 1010428317691426. |
H1299 |
Eriksson, M., et al. (2017) The effect of mutant p53 proteins on glycolysis and mitochondrial metabolism. Mol. Cell. Biol. 37, e00328-17. |
H358 |
Motooka, Y., et al. (2017) Pathobiology of Notch2 in lung cancer. Pathology 49, 486-93. |
H5 Mouse chondrocytes |
Kalev-Zylinska, M.L., et al. (2018) Altered N-methyl D-aspartate receptor subunit expression causes changes to the circadian clock and cell phenotype in osteoarthritic chondrocytes. Osteoarthr. Cartilage https://doi.org/10.1016/j.joca.2018.06.015 |
H9c2 |
Mudaliar, H, et al. (2017) Remote ischemic preconditioning attenuates EGR-1 expression following myocardial ischemia reperfusion injury through activation of the JAK-STAT pathway. Int. J. Cardiol. 228, 729-41. |
HCC |
Xu, S., et al. (2018) NFATc1 is a tumor suppressor in hepatocellular carcinoma and induces tumor cell apoptosis by activating the FasL-mediated extrinsic signaling pathway. Cancer Med. DOI: 10.1002/cam4.1716. |
HCC1569 |
Onodera, Y., et al. (2018) Arf6-driven cell invasion is intrinsically linked to TRAK1-mediated mitochondrial anterograde trafficking to avoid oxidative catastrophe. Nat. Comm. 9, 2682. |
HCC70 |
Bagu, E.T., et al. (2017) Repression of Fyn-related kinase in breast cancer cells is associated with promoter site-specific CpG methylation. Oncotarget 8, 11442-59. |
HCT 116 |
Kranz, P., et al. (2017) PDI is an essential redox-sensitive activator of PERK during the unfolded protein response (UPR). Cell Death Dis. 8, e2986. |
HCT 116 |
Lin, H., et al. (2017) DHX32 promotes angiogenesis in colorectal cancer through augmenting β-catenin signaling to induce expression of VEGFA. EBioMedicine 18, 62-72 |
HCT 116 |
Eriksson, M., et al. (2017) The effect of mutant p53 proteins on glycolysis and mitochondrial metabolism. Mol. Cell. Biol. 37, e00328-17. |
HCT-8 |
Lin, H., et al. (2017) DHX32 promotes angiogenesis in colorectal cancer through augmenting β-catenin signaling to induce expression of VEGFA. EBioMedicine 18, 62-72 |
HEK 293 |
Higashioki, K., et al. (2017) Myogenic differentiation from MYOGENIN-mutated human iPS cells by CRISPR/Cas9. Stem Cells Intl. 9210494. |
HEK 293T |
Foxler, D.E., et al. (2018) A HIF–LIMD1 negative feedback mechanism mitigates the pro‐tumorigenic effects of hypoxia. EMBO Mol. Med. 10, e8304 |
HEK 293T |
Zhang, Y., et al. (2017) Rescue of Pink1 deficiency by stress-dependent activation of autophagy. Cell Chem. Biol. 24, 471-80. |
HEK 293T |
Cerda-Opazo, P., et al. (2018) Inverse expression of survivin and reprimo correlates with poor patient prognosis in gastric cancer. Oncotarget 9, 12853-67. |
HeLa |
Monson, E.A., et al. (2018) Lipid droplet density alters the early innate immune response to viral infection. PLoS One 13, e0190597. |
HeLa |
Foxler, D.E., et al. (2018) A HIF–LIMD1 negative feedback mechanism mitigates the pro‐tumorigenic effects of hypoxia. EMBO Mol. Med. 10, e8304. |
HeLa |
Jeong, M., et al. (2017) USP8 suppresses death receptor-mediated apoptosis by enhancing FLIPL stability. Oncogene 36, 458-70. |
HeLa |
Heschen, C.L., et al. (2017) NuMA recruits dynein activity to microtubule minus-ends at mitosis. eLife 6, e29328. |
HepG2 |
Qi, Z., et al. (2017) Asiatic acid enhances Nrf2 signaling to protect HepG2 cells from oxidative damage through Akt and ERK activation. Biomed. Pharmacother. 88, 252-9 |
HepG2 |
Xu, H., et al. (2018) MicroRNA-122 supports robust innate immunity in hepatocytes by suppressing STAT3 phosphorylation. bioRχiv doi: http://dx.doi.org/10.1101/250748 |
Hs578T |
Oh, S., et al.(2017) Silencing of Glut1 induces chemoresistance via modulation of Akt/GSK-3β/β-catenin/survivin signaling pathway in breast cancer cells. Arch. Biochem. Biophys. 636, 110-22. |
Hs578T |
Onodera, Y., et al. (2018) Arf6-driven cell invasion is intrinsically linked to TRAK1-mediated mitochondrial anterograde trafficking to avoid oxidative catastrophe. Nat. Comm. 9, 2682. |
Hu5/KD3 |
Higashioki, K., et al. (2017) Myogenic differentiation from MYOGENIN-mutated human iPS cells by CRISPR/Cas9. Stem Cells Intl. 9210494 |
HuH-7 |
Monson, E.A., et al. (2018) Lipid droplet density alters the early innate immune response to viral infection. PLoS One 13, e0190597. |
HuH-7 |
Xu, H., et al. (2018) MicroRNA-122 supports robust innate immunity in hepatocytes by suppressing STAT3 phosphorylation. bioRχiv doi: http://dx.doi.org/10.1101/250747 |
HuH-7.5 |
Eyre, N.S., et al. (2017) Sensitive luminescent reporter viruses reveal appreciable release of hepatitis C virus NS5A protein into the extracellular environment. Virology 507, 20-31. |
Human primary cumulus cells |
Qiao, G., et al. (2017) Deregulation of WNT2/FZD3/β-catenin pathway compromises the estrogen synthesis in cumulus cells from patients with polycystic ovary syndrome. Biochem. Biophys. Res. Comm. 493, 847-54. |
Human foreskin fibroblasts |
Kalser, J., et al. (2017) Differences in growth properties among two human cytomegalovirus glycoprotein O genotypes. Front. Microbiol. 8, 1609. |
Human podocytes |
Fan, Y., et al. (2017) Rtn1a-mediated endoplasmic reticulum stress in podocyte injury and diabetic nephropathy. Sci. Reports 7, 323. |
Human pulmonary artery endothelial cells (HPAEC) |
Nakajima, H., et al. (2017) Flow-dependent endothelial YAP regulation contributes to vessel maintenance. Develop. Cell 40, 523-36. |
Human small airway epithelial cells (SAEC) |
Mao, P., et al. (2017) MicroRNA-19b mediates lung epithelial-mesenchymal transition via phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase in response to mechanical stretch. Am. J. Resp. Cell Mol. Biol. 56, 11-9. |
Human synovial fluid-derived mesenchymal stem cells |
Liu, W., et al. (2017) IL-1β impedes the chondrogenic differentiation of synovial fluid mesenchymal stem cells in the human temporomandibular joint. Int. J. Mol. Med. 39, 317-26.
|
Human umbilical vein endothelial cells |
Wang, J., et al. (2017) NINJ2– A novel regulator of endothelial inflammation and activation. Cell Signal. 35, 231-41. |
ICC |
Zhu, X., et al. (2017) Osthole induces apoptosis and suppresses proliferation via the PI3K/Akt pathway in intrahepatic cholangiocarcinoma. Int. J. Mol. Med. 40, 1143-51. |
iCell® cardiomyocytes
|
Hall, A.R., et al. (2018) Visualizing mutation-specific differences in the trafficking-deficient phenotype of Kv11.1 proteins linked to long QT syndrome type 2. Front. Physiol. 9, 284. |
iCell® cardiomyocytes
|
Fenix, A.M., et al. (2017) Muscle specific stress fibers give rise to sarcomeres and are mechanistically distinct from stress fibers in non-muscle cell. bioRχiv doi: https://doi.org/10.1101/235424. |
iCell® cardiomyocytes |
Taneja, N., et al. (2018) Focal adhesion kinase regulates early steps of myofibrillogenesis in cardiomyocytes. bioRχiv ; doi: http://dx.doi.org/10.1101/261248. |
IGROV1 |
Alam, S., et al. (2017) Altered (neo-) lacto series glycolipid biosynthesis impairs α2-6 sialylation on N-glycoproteins in ovarian cancer cells. Sci. Reports 7, 45367. |
Induced hepatocyte-like cells (iHeps) |
Katayama, H., et al. (2017) Generation of non-viral, transgene-free hepatocyte like cells with piggyBac transposon. Sci. Reports 7, 44498. |
INS-1 |
Spohrer, S., et al. (2017) Functional interplay between the transcription factors USF1 and PDX-1 and protein kinase CK2 in pancreatic β-cells. Sci. Reports 7, 16367 |
K562 |
Espadinha, A.-S., et al. (2017) A tyrosine kinase-STAT5-miR21-PDCD4 regulatory axis in chronic and acute myeloid leukemia cells. Oncotarget 8, 76174-88. |
MCF-10A |
Eriksson, M., et al. (2017) The effect of mutant p53 proteins on glycolysis and mitochondrial metabolism. Mol. Cell. Biol. 37, e00328-17. |
MCF7 |
Bruno, W., et al. (2017) Functional analysis of a CDKN2A 5'UTR germline variant associated with pancreatic cancer development. PLoS One 12, e0189123.
|
MCF7 |
Onodera, Y., et al. (2018) Arf6-driven cell invasion is intrinsically linked to TRAK1-mediated mitochondrial anterograde trafficking to avoid oxidative catastrophe. Nat. Comm. 9, 2682. |
MDA-MB-231 |
Oh, S., et al. (2017) Silencing of Glut1 induces chemoresistance via modulation of Akt/GSK-3β/β-catenin/survivin signaling pathway in breast cancer cells. Arch. Biochem. Biophys. 636, 110-22. |
MDA-MB-231 |
Onodera, Y., et al. (2018) Arf6-driven cell invasion is intrinsically linked to TRAK1-mediated mitochondrial anterograde trafficking to avoid oxidative catastrophe. Nat. Comm. 9, 2682. |
MDA-MB-231 |
Eriksson, M., et al. (2017) The effect of mutant p53 proteins on glycolysis and mitochondrial metabolism. Mol. Cell. Biol. 37, e00328-17. |
MDA-MB-435s |
Onodera, Y., et al. (2018) Arf6-driven cell invasion is intrinsically linked to TRAK1-mediated mitochondrial anterograde trafficking to avoid oxidative catastrophe. Nat. Comm. 9, 2682. |
MDA-MB-436 |
Onodera, Y., et al. (2018) Arf6-driven cell invasion is intrinsically linked to TRAK1-mediated mitochondrial anterograde trafficking to avoid oxidative catastrophe. Nat. Comm. 9, 2682. |
MDA-MB-438 |
Onodera, Y., et al. (2018) Arf6-driven cell invasion is intrinsically linked to TRAK1-mediated mitochondrial anterograde trafficking to avoid oxidative catastrophe. Nat. Comm. 9, 2682. |
MIN6-K8 |
Zhang, W., et al. (2017) Neuromedin U suppresses glucose-stimulated insulin secretion in pancreatic β cells. Biochem. Biophys. Res. Comm. 493, 677-83. |
MIO-M1 |
Chu-Tan, J.A., et al. (2018) MicroRNA-124 dysregulation is associated with retinal inflammation and photoreceptor death in the degenerating retina. Invest. Ophthalmol. Vis. Sci. 59, 4094-105. |
MOE |
Dean, M., Davis, D.A. and Burdette, J.E. (2017) Activin A stimulates migration of the fallopian tube epithelium, an origin of high-grade serous ovarian cancer, through non-canonical signaling. Cancer Lett. 391, 114-24. |
Mouse embryonic fibroblast |
Campostrini, G., et al. (2017) The expression of the rare caveolin-3 variant T78M alters cardiac ion channels function and membrane excitability. Cardiovasc. Res. 113, 1256-65. |
Mouse Oligodendrocyte progenitor cells (mOPC) |
Weider, M., et al. (2018) Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning. Nat. Comm. 9, 899. |
MRC4V1 |
Bertoletti, F., et al. (2017) Phosphorylation regulates human polη stability and damage bypass throughout the cell cycle. Nucl. Acids Res. 45, 9441-54. |
Murine neural stem cells |
Bansod, S., Kageyama, R., and Ohtsuka, T. (2017) Hes5 regulates the transition timing of neurogenesis and gliogenesis in mammalian neocortical development. Development 144, 3156-67. |
Murine renal tubular epithelial cells |
Yuan, X., et al. (2017) Bone mesenchymal stem cells ameliorate ischemia/reperfusion-induced damage in renal epithelial cells via microRNA-223. Stem Cell Res. Ther. 8, 146 |
NCCIT |
Park, S.-W., et al. (2017) NANOG gene expression is regulated by the ETS transcription factor ETV4 in human embryonic carcinoma NCCIT cells. Biochem. Biophys. Res. Comm.487, 532-8. |
NCI-N87 |
Cerda-Opazo, P., et al. (2018) Inverse expression of survivin and reprimo correlates with poor patient prognosis in gastric cancer. Oncotarget 9, 12853-67. |
NIH 3T3 |
Bansod, S., Kageyama, R., and Ohtsuka, T. (2017) Hes5 regulates the transition timing of neurogenesis and gliogenesis in mammalian neocortical development. Development 144, 3156-67. |
NIT-1 |
Lee, J.-J., et al. (2017) Calcium ion induced structural changes promote dimerization of secretagogin, which is required for its insulin secretory function. Sci. Reports 7, 6976. |
NMuMG |
Morita, T. and Hayashi, K. (2018) Tumor progression is mediated by thymosin-β4 through a TGFβ/MRTF signaling axis. Mol. Cancer Res. 16, 880-93. |
NOZ |
Ma, Q., et al. (2018) EMP3, which is regulated by miR-663a, suppresses gallbladder cancer progression via interference with the MAPK/ERK pathway. Cancer Lett. 430, 97-108. |
NOZ |
Hao, J., et al. (2017) Downregulation of BRD4 inhibits gallbladder cancer proliferation and metastasis and induces apoptosis via PI3K/AKT pathway. Int. J. Oncol. 51, 823-31 |
OCUG |
Ma, Q., et al. (2018) EMP3, which is regulated by miR-663a, suppresses gallbladder cancer progression via interference with the MAPK/ERK pathway. Cancer Lett. 430, 97-108. |
OCUG |
Hao, J., et al. (2017) Downregulation of BRD4 inhibits gallbladder cancer proliferation and metastasis and induces apoptosis via PI3K/AKT pathway. Int. J. Oncol. 51, 823-35 |
PANC1 |
Villarino, N., et al. (2017) A screen for inducers of bHLH activity identifies pitavastatin as a regulator of p21, Rb phosphorylation and E2F target gene expression in pancreatic cancer. Oncotarget 8, 53154-67. |
PBMC |
Cai, F., et al. (2018) MicroRNA-146b-3p regulates the development and progression of cerebral infarction with diabetes through RAF1/P38MAPK/COX-2 signaling pathway. Am. J. Transl. Res. 10, 618-28. |
PC3 |
Xu, H., et al. (2018) MicroRNA-122 supports robust innate immunity in hepatocytes by suppressing STAT3 phosphorylation. bioRχiv doi: http://dx.doi.org/10.1101/250746 |
PtK2 |
Long, A.F., Udy, D.B., and Dumont, S. (2017) Hec1 tail phosphorylation differentially regulates mammalian kinetochore coupling to polymerizing and depolymerizing microtubules. Curr. Biol. 27, 1692-9. |
PtK2 |
Heschen, C.L., et al. (2017) NuMA recruits dynein activity to microtubule minus-ends at mitosis. eLife 6, e29328. |
RAW264.7 |
Ricci, E., et al. (2017) Role of the glucocorticoid-induced leucine zipper gene in dexamethasone-induced inhibition of mouse neutrophil migration via control of annexin A1 expression. FASEB J. 31, 3054-65. |
RMC |
Gao, H.-Y. and Han, C.-X. (2017) The role of PTEN up-regulation in suppressing glomerular mesangial cells proliferation and nephritis pathogenesis. Eur. Rev. Med. Pharmacol. Sci. 21, 3634-41. |
RPE1 |
Heschen, C.L., et al. (2017) NuMA recruits dynein activity to microtubule minus-ends at mitosis. eLife 6, e29328. |
SaOS2 |
Nishita, M., et al. (2017) Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness. Sci. Reports 7, 1. |
SGC-996 |
Ma, Q., et al. (2018) EMP3, which is regulated by miR-663a, suppresses gallbladder cancer progression via interference with the MAPK/ERK pathway. Cancer Lett. 430, 97-108. |
SGC-996 |
Hao, J., et al. (2017) Downregulation of BRD4 inhibits gallbladder cancer proliferation and metastasis and induces apoptosis via PI3K/AKT pathway. Int. J. Oncol. 51, 823-34 |
SH-SY5Y |
Zhang, Y., et al. (2017) Rescue of Pink1 deficiency by stress-dependent activation of autophagy. Cell Chem. Biol. 24, 471-80. |
SK-BR-3 |
Onodera, Y., et al. (2018) Arf6-driven cell invasion is intrinsically linked to TRAK1-mediated mitochondrial anterograde trafficking to avoid oxidative catastrophe. Nat. Comm. 9, 2682. |
SK-HEP-1 |
McDonald, C.J., et al. (2018) Evaluation of a bone morphogenetic protein 6 variant as a cause of iron loading. Hum. Genom. 12, 23. |
SKOV3 |
Yan, X.-Y., et al. (2017) p62/SQSTM1 as an oncotarget mediates cisplatin resistance through activating RIP1-NF-κB pathway in human ovarian cancer cells. Cancer Sci. 108, 1405-13. |
SKOV3 |
Lu, T., et al. (2018) Blockade of ONECUT2 expression in ovarian cancer inhibited tumor cell proliferation, migration, invasion and angiogenesis. Cancer Sci. 109, 2221-34. |
SKOV3 |
Alam, S., et al. (2017) Altered (neo-) lacto series glycolipid biosynthesis impairs α2-6 sialylation on N-glycoproteins in ovarian cancer cells. Sci. Reports 7, 45367. |
SNU-1 |
Cerda-Opazo, P., et al. (2018) Inverse expression of survivin and reprimo correlates with poor patient prognosis in gastric cancer. Oncotarget 9, 12853-67 |
SW480 |
Lin, H., et al. (2017) DHX32 promotes angiogenesis in colorectal cancer through augmenting β-catenin signaling to induce expression of VEGFA. EBioMedicine 18, 62-72 |
SW620 |
Lin, H., et al. (2017) DHX32 promotes angiogenesis in colorectal cancer through augmenting β-catenin signaling to induce expression of VEGFA. EBioMedicine 18, 62-72 |
THP-1 |
Wiśnik, E., Płoszaj, T. and Robaszkiewicz, A. (2017) Downregulation of PARP1 transcription by promoter-associated E2F4-RBL2-HDAC1-BRM complex contributes to repression of pluripotency stem cell factors in human monocytes. Sci. Reports 7, 9483. |
TT |
Jang, S., et al. (2017) Histone deacetylase inhibitor thailandepsin-A activates Notch signaling and suppresses neuroendocrine cancer cell growth in vivo. Oncotarget 8, 70828-40. |
U2OS |
Foxler, D.E., et al. (2018) A HIF–LIMD1 negative feedback mechanism mitigates the pro‐tumorigenic effects of hypoxia. EMBO Mol. Med. 10, e8304. |
U2OS |
Nishita, M., et al. (2017) Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness. Sci. Reports 7, 1. |
U373MG |
Kwon, R.-J., et al.(2017) Roles of zinc-fingers and homeoboxes 1 during the proliferation, migration, and invasion of glioblastoma cells. Tumor Biol. 39, 1010428317694575. |
U87 |
Diplas, B.H., et al. (2018) The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma. Nat. Comm. 9, 2087. |
UACC-62 |
Jeong, M., et al. (2017) USP8 suppresses death receptor-mediated apoptosis by enhancing FLIPL stability. Oncogene 36, 458-70. |
WI-38 |
Eriksson, M., et al. (2017) The effect of mutant p53 proteins on glycolysis and mitochondrial metabolism. Mol. Cell. Biol. 37, e00328-17. |