EXO-NET® Pan-Exosome Capture and Nucleic Acid Extraction Solutions

Exosomes are small extracellular vesicles, ranging in size from 30–150 nanometers. Released by a variety of cell types, exosomes play a crucial role in intercellular communication. These vesicles carry an array of molecules, including proteins, lipids and nucleic acids that reflect an exosome's cell of origin and can influence the behavior of recipient cells. Exosome research is dynamic and includes understanding their basic biology, developing detection and quantification techniques, and exploring their use in regenerative medicine and cancer therapy. Purifying exosomes previously required time-consuming manual methods.

The EXO-NET® Pan Exosome Capture Tool automates exosome isolation from a variety of biological samples. Using a unique capture mechanism, this tool helps researchers efficiently isolate exosomes with a high degree of purity and integrity. These are critical parameters for subsequent analyses in biomarker research, cellular communication studies and disease pathogenesis investigations.

EXO-NET® Pan-Exosome Capture + ReliaPrep™ FFPE Total RNA Miniprep System

For low sample numbers, manually isolate exosomes from plasma using the EXO-NET® Pan-Exosome Capture system, and purify total RNA including miRNA using the ReliaPrep™ FFPE Total RNA Miniprep System.

Download protocol and data: Manual Total RNA Purification from Exosomes

EXO-NET® Pan-Exosome Capture + Maxwell® miRNA Plasma and Serum Kit

For medium sample numbers, isolate exosomes from plasma using the EXO-NET® Pan-Exosome Capture system, and purify total RNA including miRNA using the Maxwell® RSC miRNA Plasma and Serum Kit on the Maxwell® RSC Instrument.

Download protocol and data: Automated Total RNA Purification from Exosomes

Maxwell® HT EXO-NET® Pan-Exosome miRNA Kit

For high throughput samples, isolate exosomes from plasma using the all-in-one Maxwell® HT EXO-NET® Pan-Exosome miRNA Kit on the KingFisher™ Apex or Flex Instruments.

Detection of RNA Purified from Exosomes Isolated from Plasma Processed on KingFisher™ Instruments