Real-Time Live-Cell Imaging and Analysis for Drug Discovery

In this webinar, you will learn:

How live-cell kinetic detection reagents work
How to generate kinetic multiplex data using a multimode plate reader with live cell imaging capabilities
How to streamline and simplify the recording of dose- and time response curves for drug toxicity testing
How to interpret live-cell kinetic data to better understand dynamics (or "dynamic processes") in apoptosis

Summary

Time- and dose-dependent analysis of cellular responses to drug treatments is critical in the drug discovery and characterization process. Here we present, how you can easily collect comprehensive time point data from a single sample well using live-cell, real-time detection reagents in combination with a multimodal plate reader that includes environmental control and cell imaging features.

Join researchers from Promega and Tecan to learn how to harness these new live-cell kinetic tools in your drug discovery research. We will present data on evaluating multiple small molecule inducers of apoptosis by measuring phosphatidylserine exposure, membrane permeability, and morphology changes in real-time.

Speakers

Terry Riss, PhD
Senior Product Manager, Cell Health
Promega Corporation

Dr. Terry Riss started the Cell Biology program at Promega Corporation in 1990 and held several R&D and Project Management positions since. Dr. Riss managed development of cell viability, cytotoxicity, apoptosis, and protease assay systems and also lead efforts to identify and promote multiplexing of cell-based assays to determine the mechanism of cell death. Dr. Riss now serves as Senior Product Manager, Cell Health involved in outreach educational training activities including validating assay systems applied to 3D cell culture models. Dr. Riss also serves as an editor of the In Vitro Cell-Based Assays section of the Assay Guidance Manual hosted by The National Center for Advancing Translational Sciences (NCATS) at the NIH.

Christian Oberdanner, PhD
Senior Applications Specialist
Tecan

Christian Oberdanner, PhD, is a Senior Application Specialist at Tecan Austria. He studied molecular biology at the University of Salzburg, with a strong focus on cell and tumor biology. Christian started working for Tecan Austria as an external scientific consultant in 2005, and joined the company permanently in 2006. Since then, he has held several roles, including Application Scientist, Application Specialist and Product Manager. Christian’s priorities within Tecan are multimode microplate reader applications and cell imaging.

Real-Time Live-Cell Imaging and Analysis for Drug Discovery

Summary

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