TRAP1, TNF receptor associated protein 1

TRAP1, TNF receptor associated protein 1

• This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

• Gene Synonyms (heat shock protein 75 kDa, mitochondrial, TNFR-associated protein 1, testicular tissue protein Li 209, tumor necrosis factor type 1 receptor-associated protein, HSP 75, HSP75, HSP90L, TRAP-1,)
• NCBI Gene ID: 10131
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A140VJY2
  UNIPROT ID#>>Q12931
  UNIPROT ID#>>Q53FS6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TNF receptor associated protein 1 interacts with:

• aminoadipate aminotransferase
  anoctamin 7
  anterior gradient 2, protein disulphide isomerase family member
  ariadne RBR E3 ubiquitin protein ligase 2
  autophagy related 16 like 1
  bromodomain containing 7
  centrosomal protein 250
  centrosomal protein 72
  cleavage and polyadenylation specific factor 6
  coenzyme Q2, polyprenyltransferase
  coenzyme Q3, methyltransferase
  coiled-coil domain containing 8
  cornulin
  developmental pluripotency-associated 3
  DnaJ heat shock protein family (Hsp40) member C11
  DnaJ heat shock protein family (Hsp40) member C8
  DND microRNA-mediated repression inhibitor 1
  ER degradation enhancing alpha-mannosidase like protein 3
  ESX homeobox 1
  eukaryotic translation initiation factor 2 alpha kinase 4
  expressed sequence AI837181
  FANCD2 and FANCI associated nuclease 1
  F-box protein 6
  HEXIM P-TEFb complex subunit 1
  hydroxysteroid dehydrogenase like 2
  La ribonucleoprotein 7, transcriptional regulator
  MAGE family member D2
  methyltransferase like 14
  microcephalin 1
  myosin light chain 12B
  N-acetylneuraminate synthase
  nuclear RNA export factor 1
  obscurin like cytoskeletal adaptor 1
  opioid growth factor receptor
  Parkinsonism associated deglycase
  peroxiredoxin 5
  phosphoethanolamine/phosphocholine phosphatase 1
  pleckstrin homology domain containing A4
  protein phosphatase 6, regulatory subunit 1
  PTEN induced kinase 1
  receptor interacting serine/threonine kinase 4
  SNW domain containing 1
  spindle apparatus coiled-coil protein 1
  splicing factor 3a subunit 1
  splicing factor 3a subunit 3
  staphylococcal nuclease and tudor domain containing 1
  testin LIM domain protein
  thioredoxin reductase 2
  TNFAIP3 interacting protein 2
  toll like receptor 6
  TRAF3 interacting protein 1
  transmembrane protein 41B
  ubiquilin 2
  ubiquitin fold modifier 1
  vir like m6A methyltransferase associated
  WD repeat and HMG-box DNA binding protein 1
  WW domain containing oxidoreductase
  Yes1 associated transcriptional regulator
  zinc finger FYVE-type containing 21

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.