NUP50, nucleoporin 50

NUP50, nucleoporin 50

• The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (NPAP60, NPAP60L, nuclear pore complex protein Nup50, 50 kDa nucleoporin, nuclear pore-associated protein 60L, nucleoporin 50kD, nucleoporin 50kDa, nucleoporin Nup50,)
• NCBI Gene ID: 10762
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UKX7
  UNIPROT ID#>>A0A024R4X7
  UNIPROT ID#>>B4E2D3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nucleoporin 50 interacts with:

• antigen identified by monoclonal antibody Ki 67
  AT-rich interaction domain 2
  B9 domain containing 2
  biorientation of chromosomes in cell division 1 like 1
  bromodomain containing 7
  CDV3 homolog
  cell division cycle associated 2
  coiled-coil domain containing 22
  CXXC finger protein 1
  eukaryotic translation initiation factor 4E nuclear import factor 1
  F-box and WD repeat domain containing 11
  F-box protein 28
  HSPA (Hsp70) binding protein 1
  karyopherin subunit alpha 6
  kelch like family member 7
  kinesin family member 18B
  kinesin family member C1
  kinesin family member C5B
  MRG domain binding protein
  nischarin
  nucleoporin 107
  nucleoporin 107
  nucleoporin 133
  nucleoporin 160
  nucleoporin 35
  nucleoporin 43
  nucleoporin 85
  nucleoporin 98
  PHD finger protein 10
  pleckstrin homology domain containing A4
  polybromo 1
  RAN binding protein 2
  regulator of chromosome condensation 1
  SBDS ribosome maturation factor
  SLX4 structure-specific endonuclease subunit
  sosondowah ankyrin repeat domain family member A
  SUZ12 polycomb repressive complex 2 subunit
  torsin 1A interacting protein 1
  ubiquitin associated protein 2
  ubiquitin-conjugating enzyme E2I
  vir like m6A methyltransferase associated
  WASH complex subunit 4
  WD repeat and HMG-box DNA binding protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.