WASF3, WASP family member 3

WASF3, WASP family member 3

• This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. A pseudogene of this gene have been defined on chromosome 6. Alternative splicing results in multiple transcript variants [provided by RefSeq, May 2014]

• Gene Synonyms (Brush-1, SCAR3, WAVE3, wiskott-Aldrich syndrome protein family member 3, WAS protein family member 3, WASP family Verprolin-homologous protein 3, protein WAVE-3, verprolin homology domain-containing protein 3,)
• NCBI Gene ID: 10810
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UPY6
  UNIPROT ID#>>Q5T8P4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

WASP family member 3 interacts with:

• BRICK1 subunit of SCAR/WAVE actin nucleating complex
  cap methyltransferase 1
  cytoplasmic FMR1 interacting protein 1
  cytoplasmic FMR1 interacting protein 2
  FRA10A associated CGG repeat 1
  KIAA1217
  KN motif and ankyrin repeat domains 2
  RAS protein activator like 3
  TNFAIP3 interacting protein 2
  translocase of inner mitochondrial membrane 50
  vir like m6A methyltransferase associated
  WASH complex subunit 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.