PTGDR2, prostaglandin D2 receptor 2

PTGDR2, prostaglandin D2 receptor 2

• This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011]

• Gene Synonyms (prostaglandin D2 receptor 2, G-protein coupled receptor 44, chemoattractant receptor homologous molecule expressed on T helper type 2 cells, chemoattractant receptor-homologous molecule expressed on TH2 cells, putative G-protein coupled receptor 44, CD294, CRTH2, DL1R, DP2, GPR44,)
• NCBI Gene ID: 11251
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y5Y4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

prostaglandin D2 receptor 2 interacts with:

• ankyrin repeat domain 13C
  JNK1/MAPK8 associated membrane protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.