ACSL6, acyl-CoA synthetase long chain family member 6

ACSL6, acyl-CoA synthetase long chain family member 6

• The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2011]

• Gene Synonyms (ACS2, FACL6, LACS 6, LACS2, LACS5, long-chain-fatty-acid--CoA ligase 6, arachidonate--CoA ligase, fatty-acid-Coenzyme A ligase, long-chain 6, long fatty acyl-CoA synthetase 2,)
• NCBI Gene ID: 23305
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B2RB13
  UNIPROT ID#>>Q9UKU0
  UNIPROT ID#>>B4DFW3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

acyl-CoA synthetase long chain family member 6 interacts with:

• acyl-CoA synthetase long chain family member 6
  protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
  zinc finger protein 655

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.