VPS39, VPS39 subunit of HOPS complex

VPS39, VPS39 subunit of HOPS complex

• This gene encodes a protein that may promote clustering and fusion of late endosomes and lysosomes. The protein may also act as an adaptor protein that modulates the transforming growth factor-beta response by coupling the transforming growth factor-beta receptor complex to the Smad pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

• Gene Synonyms (TLP, VAM6, hVam6p, vam6/Vps39-like protein, TRAP1-like protein, VPS39, HOPS complex subunit, vacuolar protein sorting 39 homolog,)
• NCBI Gene ID: 23339
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R9L9
  UNIPROT ID#>>Q96JC1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

VPS39 subunit of HOPS complex interacts with:

• epsin 3
  hook microtubule tethering protein 1
  protein prenyltransferase alpha subunit repeat containing 1
  Rab interacting lysosomal protein
  ribosomal protein S6 kinase C1
  spermatogenesis associated 1
  syntaxin 17
  tuftelin interacting protein 11
  ubiquitin specific peptidase 54
  UBX domain protein 6
  vir like m6A methyltransferase associated
  VPS11 core subunit of CORVET and HOPS complexes
  VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
  VPS39 subunit of HOPS complex
  zinc finger containing ubiquitin peptidase 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.