IL1RAP, interleukin 1 receptor accessory protein

IL1RAP, interleukin 1 receptor accessory protein

• This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Jul 2018]

• Gene Synonyms (interleukin-1 receptor accessory protein, IL-1 receptor accessory protein, interleukin-1 receptor 3, interleukin-1 receptor accessory protein beta, C3orf13, IL-1RAcP, IL1R3,)
• NCBI Gene ID: 3556
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NPH3
  UNIPROT ID#>>A8K6K4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

interleukin 1 receptor accessory protein interacts with:

• cyclin I
  hepatitis A virus cellular receptor 2
  interleukin 1 receptor associated kinase 1
  interleukin 1 receptor type 2
  interleukin 1 receptor, type II
  interleukin 18 receptor 1
  karyopherin subunit alpha 1
  KRAS proto-oncogene, GTPase
  melanocortin 4 receptor
  membrane associated ring-CH-type finger 8
  MYD88 innate immune signal transduction adaptor
  phosphoinositide-3-kinase regulatory subunit 1
  pre-mRNA processing factor 40 homolog A
  protein kinase C iota
  protein tyrosine phosphatase receptor type D
  protein tyrosine phosphatase receptor type F
  protein tyrosine phosphatase receptor type S
  protocadherin alpha 12
  protocadherin gamma subfamily B, 4
  Rac family small GTPase 1
  signal regulatory protein alpha
  signal transducer and activator of transcription 3
  TIR domain containing adaptor protein
  toll interacting protein
  toll like receptor adaptor molecule 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.